IsaacIsaacSeason 12005 · 56 episodesEpisodes1Mandy Moore2Keira Knightley3Elle MacPherson4Wynonna Judd5Amanda Bynes6Lee Ann Womack7The Sopranos' Steve Schirripa8Jon Favreau9Rob and Amber from Survivor10Carla Gugino & Elisabeth Hasselbeck11Tom Arnold12Shania Twain13Niecy Nash14Andie MacDowell15Sarah Jessica Parker16Rachael Ray17Selma Blair18Matthew Modine19Rent's Anthony Rapp20Gastineau Girls21Isaac Makes You Fashion Fabulous22Madonna23Finola Hughes24Isaac and the City25Sela WardSela Ward; Jaime Pressly. Also: a segment on ice-cream recipes.26Andrew Firestone27Rob Morrow28Cynthia Nixon29Nia Long30Bo Bice & Shannon Elizabeth31Margaret Cho32Michael Moloney33Kimora Lee Simmons34Isaac's Glamour Girls35Iman36Isaac Strikes Again37Rosie Perez38Lisa Loeb39S. Epatha Merkerson & J.C. Chasez40Gabrielle Union41Isaac's It Girls42Jamie Lynn Sigler43Gina Gershon44Huey Lewis45Tony Danza46Isaac's Famous Friends47Isaac's TV Darlings48Isaac's Celebrity Field Trips49Keira Knightley50Selma Blair51Niecy Nash52Finola Hughes53Madonna54Gastineau Girls55Lisa Loeb56Jamie Lynn SiglerSeason 2